Does speed of intrathecal injection affect the distribution of 0.5% hyperbaric bupivacaine?

Does speed of intrathecal injection affect the distribution of 0.5% hyperbaric bupivacaine?

We have evaluated the influence of speed of intrathecal injection on lateral distribution of 0.5% hyperbaric bupivacaine. We studied 60 patients undergoing lower limb surgery who were placed in the lateral position with the operative side in the dependent position. After dural puncture (25-gauge Whitacre spinal needle), the needle aperture was turned towards the dependent side and 0.5% hyperbar...

Does Adding Lidocaine to Intrathecal Bupivacaine Affect Hemodynamic Parameters during Hip Fracture Surgery?

Background: Hip fracture is one of the most common problems in elderly that needs surgical repair. As, the majority ofthese patients have chronic diseases, they are at increased risk of peri-operative mortality and morbidity. The purposeof this study was to evaluate spinal anesthesia with bupivacaine vs bupivacaine in combination with lidocaine in termsof hemodynamic changes in patients undergo...

Circadian Effects on Neural Blockade of Intrathecal Hyperbaric Bupivacaine

BACKGROUND Circadian variations in the absorption, distribution, protein binding, elimination and metabolism of drugs account for many of the administration-time-dependent differences in their pharmacokinetics. The aim of this study is to determine whether the time of intrathecal injection influences spinal anesthesia. METHODS Ninety patients scheduled for orthopedic surgery were randomly ass...

Study on Comparing Intrathecal Hyperbaric Bupivacaine and Isobaric Bupivacaine In Common Surgical Procedures without Adjunct

A Randomised Controlled Study Comparing Intrathecal Hyperbaric Bupivacaine And Isobaric Bupivacaine In Common Urological Procedures